Mouse anti‑Rat CD86 IgG1 Monoclonal RW-C188422-0.5
Antibody: CD86 Mouse anti-Rat Monoclonal (Low Endotoxin) (24F) Antibody, Application: IHC-Fr, IP, Flo, Reactivity: Rat, Format: Unconjugated, Low Endotoxin, Descriptio: CD86 antibody RW-C188422 is an unconjugated mouse monoclonal antibody to rat CD86. Validated for Flow, IHC and IP., Targe: Rat CD86, Synonym: CD86 | Activation B7-2 antigen | B7-2 | B7.2 | B70 | CD86 molecule | CTLA-4 counter-receptor B7.2 | CD86 antigen | FUN-1 | LAB72 | BU63 | CD28LG2 | Ctla-4 counter-receptors b7.2, Hos: Mouse, Reactivit: Rat (tested or 100% immunogen sequence identity), Clonalit: IgG1 Monoclonal, Clon: 24F, Conjugation: Unconjugated, Purificatio: Protein G purified, Modification: Low Endotoxin, Immunoge: HTLV-1 transformed Lewis - S1 cells., Specificit: Recognizes rat CD86, otherwise known as B7-2, a type I transmembrane protein and member of the Ig superfamily, which acts as a ligand for both CD28 and CD152 (CTLA-4), and is primarily expressed on antigen presenting cells (APCs) including dendritic cells, and also on germinal centre B cells and macrophages. Like CD80, CD86 is an accessory molecule which functions in the CD28-CD80/CD86 co-stimulatory pathway, vital for T cell activation, crosstalk between T and B cells, and Th2-mediated Ig production. Clone 24F has been shown to block the co-stimulatory activity of rat CD86., Application: IHC - Frozen
Immunoprecipitation
Flow Cytometry (1:25 - 1:200), Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more: None, Usag: The applications listed have been tested for the unmodified form of this product. Other forms have not been tested., Presentatio: PBS, Storag: Store at -20°C. Store undiluted. Avoid freeze-thaw cycles. Microcentrifugation recommended if solution contains precipitate., Restriction: For research use only. Intended for use by laboratory professionals., Guarante: This antibody carries the RW 100% Guarantee., About CD8: Uniprot: P42081 NCBI: NM_006889 NP_008820.3