Bcl-2 Rabbit pAb

Enables BH domain binding activity. Involved in several processes, including response to peptide; response to purine-containing compound; and response to vitamin. Located in cytosol; mitochondrial crista; and perinuclear region of cytoplasm. Used to study several disorders, including brain ischemia (multiple); end stage renal disorder; gastric ulcer; intestinal disorder (multiple); and status epilepticus. Biomarker of several disorders, including abdominal obesity-metabolic syndrome 1; brain disorder (multiple); hypertension (multiple); intrinsic cardiomyopathy (multiple); and neurodegenerative disorder (multiple). Human ortholog(s) of this gene implicated in several disorders, including carcinoma (multiple); hematologic cancer (multiple); intracranial aneurysm; prostate cancer; and urinary bladder cancer. Orthologous to human BCL2 (BCL2 apoptosis regulator).